dextromoramide Indications/Contra | FAERs | Orange Book | BioActivity |

Stem definitionDrug idCAS RN
843 357-56-2

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • dextromoramide
  • moramide
  • pyrrolamidol
  • pyrrolamidolum
  • dextromoramide tartrate
An opioid analgesic structurally related to METHADONE and used in the treatment of severe pain. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1070)
  • Molecular weight: 392.54
  • Formula: C25H32N2O2
  • CLOGP: 4.07
  • LIPINSKI: 0
  • HAC: 4
  • HDO: 0
  • TPSA: 32.78
  • ALOGS: -4.35
  • ROTB: 6

Drug dosage:

DoseUnitRoute
20 mg O
20 mg P
40 mg R

Approvals:

None

FDA Adverse Event Reporting System

None

Pharmacologic Action:

SourceCodeDescription
ATC N02AC01 NERVOUS SYSTEM
ANALGESICS
OPIOIDS
Diphenylpropylamine derivatives
MeSH PA D000700 Analgesics
MeSH PA D000701 Analgesics, Opioid
MeSH PA D002491 Central Nervous System Agents
MeSH PA D002492 Central Nervous System Depressants
MeSH PA D009294 Narcotics
MeSH PA D018373 Peripheral Nervous System Agents
MeSH PA D018689 Sensory System Agents
CHEBI has role CHEBI:35482 opioid analgesic

Drug Use (View source of the data)

DiseaseRelationSNOMED_IDDOID
Severe pain indication 76948002

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 6.5 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
N0000167041 NUI
C0011817 UMLSCUI
D07287 KEGG_DRUG
CHEMBL431928 ChEMBL_ID
N0000167041 NDFRT
003694 NDDF
96191003 SNOMEDCT_US
3290 RXNORM
387561007 SNOMEDCT_US
9S4S6CIY83 UNII
733 INN_ID
92943 PUBCHEM_CID
D003916 MESH_DESCRIPTOR_UI
DB01529 DRUGBANK_ID
2922-44-3 SECONDARY_CAS_RN
CHEMBL3833311 ChEMBL_ID
CHEMBL3833389 ChEMBL_ID
CHEBI:74274 CHEBI

Pharmaceutical products:

None