Gamma-aminobutyric acid type B receptor subunit 1

Description:

Description
  • Accession: Q9Z0U4
  • Swissprot: GABR1_RAT
  • Organism: Rattus norvegicus
  • Gene: Gabbr1
  • Target classes: GPCR, Unclassified

Drug Relations:

baclofen
A GAMMA-AMINOBUTYRIC ACID derivative that is a specific agonist of GABA-B RECEPTORS. It is used in the treatment of MUSCLE SPASTICITY, especially that due to SPINAL CORD INJURIES. Its therapeutic effects result from actions at spinal and supraspinal sites, generally the reduction of excitatory transmission. Bioactivity details MOA