Protein arginine N-methyltransferase 1


  • Accession: Q99873
  • Swissprot: ANM1_HUMAN
  • Organism: Homo sapiens
  • Gene: PRMT1
  • Target class: Enzyme

Drug Relations:

Physiologic methyl radical donor involved in enzymatic transmethylation reactions and present in all living organisms. It possesses anti-inflammatory activity and has been used in treatment of chronic liver disease. (From Merck, 11th ed) Bioactivity details MOA
Bioactivity details MOA
A phthalic indicator dye that appears yellow-green in normal tear film and bright green in a more alkaline medium such as the aqueous humor. Bioactivity details MOA
A polyanionic compound with an unknown mechanism of action. It is used parenterally in the treatment of African trypanosomiasis and it has been used clinically with diethylcarbamazine to kill the adult Onchocerca. (From AMA Drug Evaluations Annual, 1992, p1643) It has also been shown to have potent antineoplastic properties. Bioactivity details MOA