Smoothened homolog

Description:

Description
  • Accession: Q99835
  • Swissprot: SMO_HUMAN
  • Organism: Homo sapiens
  • Gene: SMO
  • Target class: GPCR

Drug Relations:

glasdegib
Glasdegib is an inhibitor of the Hedgehog pathway. Glasdegib binds to and inhibits Smoothened, a transmembrane protein involved in hedgehog signal transduction. Bioactivity details MOA
sonidegib
specific Smoothened/Smo antagonist Bioactivity details MOA
vismodegib
inhibits the hedgehog pathway and ABC transporters; has antineoplastic activity Bioactivity details MOA