P2X purinoceptor 4

Description:

Description
  • Accession: Q99571
  • Swissprot: P2RX4_HUMAN
  • Organism: Homo sapiens
  • Gene: P2RX4
  • Target class: Ion channel

Drug Relations:

adenosine triphosphate
An adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter. Bioactivity details MOA
paroxetine
A serotonin uptake inhibitor that is effective in the treatment of depression. Bioactivity details MOA
suramin
A polyanionic compound with an unknown mechanism of action. It is used parenterally in the treatment of African trypanosomiasis and it has been used clinically with diethylcarbamazine to kill the adult Onchocerca. (From AMA Drug Evaluations Annual, 1992, p1643) It has also been shown to have potent antineoplastic properties. Bioactivity details MOA