Egl nine homolog 2


  • Accession: Q96KS0
  • Swissprot: EGLN2_HUMAN
  • Organism: Homo sapiens
  • Gene: EGLN2
  • Target class: Enzyme

Drug Relations:

Roxadustat is a first-in-class orally administered inhibitor of hypoxia-inducible factor (HIF) prolylhydroxylase that corrects anemia by activating a response that occurs naturally when the body responds to reduced oxygen levels in the blood. The response activated by roxadustat involves the regulation of multiple, complementary processes to promote erythropoiesis and increase the blood’s oxygen-carrying capacity. Bioactivity details MOA