Potassium voltage-gated channel subfamily G member 3

Description:

Description
  • Accession: Q8TAE7
  • Swissprot: KCNG3_HUMAN
  • Organism: Homo sapiens
  • Gene: KCNG3
  • Target class: Ion channel

Drug Relations:

amifampridine
4-Aminopyridine derivative that acts as a POTASSIUM CHANNEL blocker to increase release of ACETYLCHOLINE from nerve terminals. It is used in the treatment of CONGENITAL MYASTHENIC SYNDROMES. Bioactivity details MOA
fampridine
One of the POTASSIUM CHANNEL BLOCKERS with secondary effect on calcium currents which is used mainly as a research tool and to characterize channel subtypes. Bioactivity details MOA
guanidine
A strong organic base existing primarily as guanidium ions at physiological pH. It is found in the urine as a normal product of protein metabolism. It is also used in laboratory research as a protein denaturant. (From Martindale, the Extra Pharmacopoeia, 30th ed and Merck Index, 12th ed) It is also used in the treatment of myasthenia and as a fluorescent probe in HPLC. Bioactivity details MOA