Uracil nucleotide/cysteinyl leukotriene receptor


  • Accession: Q6NS65
  • Swissprot: GPR17_MOUSE
  • Organism: Mus musculus
  • Gene: Gpr17
  • Target class: Unclassified

Drug Relations:

Cangrelor is a direct P2Y12 platelet receptor inhibitor that blocks ADP-induced platelet activation and aggregation. Cangrelor binds selectively and reversibly to the P2Y12 receptor to prevent further signaling and platelet activation. Bioactivity details MOA
Montelukast is an orally active compound that binds with high affinity and selectivity to the CysLT1 receptor (in preference to other pharmacologically important airway receptors, such as the prostanoid, cholinergic, or beta-adrenergic receptor). Montelukast inhibits physiologic actions of cysteinyl leukotriene LTD4 at the CysLT1 receptor without any agonist activity. Bioactivity details MOA