Neuronal acetylcholine receptor subunit alpha-2

Description:

Description
  • Accession: Q15822
  • Swissprot: ACHA2_HUMAN
  • Organism: Homo sapiens
  • Gene: CHRNA2
  • Target class: Ion channel

Drug Relations:

alcuronium
A non-depolarizing skeletal muscle relaxant similar to TUBOCURARINE. It is used as an anesthesia adjuvant, for endotracheal intubation and to produce muscle relaxation in general anesthesia during surgical procedures. Bioactivity details MOA
atracurium
A non-depolarizing neuromuscular blocking agent with short duration of action. Its lack of significant cardiovascular effects and its lack of dependence on good kidney function for elimination provide clinical advantage over alternate non-depolarizing neuromuscular blocking agents. Bioactivity details MOA
biperiden
A muscarinic antagonist that has effects in both the central and peripheral nervous systems. It has been used in the treatment of arteriosclerotic, idiopathic, and postencephalitic parkinsonism. It has also been used to alleviate extrapyramidal symptoms induced by phenothiazine derivatives and reserpine. Bioactivity details MOA
carbamazepine
A dibenzazepine that acts as a sodium channel blocker. It is used as an anticonvulsant for the treatment of grand mal and psychomotor or focal SEIZURES. It may also be used in the management of BIPOLAR DISORDER, and has analgesic properties. Bioactivity details MOA
cotinine
The N-glucuronide conjugate of cotinine is a major urinary metabolite of NICOTINE. It thus serves as a biomarker of exposure to tobacco SMOKING. It has CNS stimulating properties. Bioactivity details MOA
dimethyltubocurarinium
from Chinese herb Cyclea hainanensis Mrr Bioactivity details MOA
doxacurium
according to Unlisted Drugs, BW-A938U is a bis-benzylisoquinolinium diester and a highly potent neuromuscular blocker Bioactivity details MOA
mecamylamine
A nicotinic antagonist that is well absorbed from the gastrointestinal tract and crosses the blood-brain barrier. Mecamylamine has been used as a ganglionic blocker in treating hypertension, but, like most ganglionic blockers, is more often used now as a research tool. Bioactivity details MOA
methohexital
An intravenous anesthetic with a short duration of action that may be used for induction of anesthesia. Bioactivity details MOA
mivacurium
An isoquinoline derivative that is used as a short-acting non-depolarizing agent. Bioactivity details MOA
nicotine
Devices or delivery systems used to aid in ending a TOBACCO habit. Bioactivity details MOA
pipecuronium
A piperazinyl androstane derivative which is a non-depolarizing neuromuscular blocking agent (NEUROMUSCULAR NONDEPOLARIZING AGENTS). It is used as a muscle relaxant during ANESTHESIA and surgical procedures. Bioactivity details MOA
tubocurarine
A neuromuscular blocker and active ingredient in CURARE; plant based alkaloid of Menispermaceae. Bioactivity details MOA
vecuronium
Monoquaternary homolog of PANCURONIUM. A non-depolarizing neuromuscular blocking agent with shorter duration of action than pancuronium. Its lack of significant cardiovascular effects and lack of dependence on good kidney function for elimination as well as its short duration of action and easy reversibility provide advantages over, or alternatives to, other established neuromuscular blocking agents. Bioactivity details MOA