Nicotinate-nucleotide pyrophosphorylase [carboxylating]


  • Accession: Q15274
  • Swissprot: NADC_HUMAN
  • Organism: Homo sapiens
  • Gene: QPRT
  • Target class: Enzyme

Drug Relations:

An important compound functioning as a component of the coenzyme NAD. Its primary significance is in the prevention and/or cure of blacktongue and PELLAGRA. Most animals cannot manufacture this compound in amounts sufficient to prevent nutritional deficiency and it therefore must be supplemented through dietary intake. Bioactivity details MOA
nicotinic acid
A water-soluble vitamin of the B complex occurring in various animal and plant tissues. It is required by the body for the formation of coenzymes NAD and NADP. It has PELLAGRA-curative, vasodilating, and antilipemic properties. Bioactivity details MOA