Uracil nucleotide/cysteinyl leukotriene receptor


  • Accession: Q13304
  • Swissprot: GPR17_HUMAN
  • Organism: Homo sapiens
  • Gene: GPR17
  • Target class: GPCR

Drug Relations:

adenosine triphosphate
An adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter. Bioactivity details MOA
Montelukast is an orally active compound that binds with high affinity and selectivity to the CysLT1 receptor (in preference to other pharmacologically important airway receptors, such as the prostanoid, cholinergic, or beta-adrenergic receptor). Montelukast inhibits physiologic actions of cysteinyl leukotriene LTD4 at the CysLT1 receptor without any agonist activity. Bioactivity details MOA
SRS-A antagonist; leukotriene D4 receptor antagonist Bioactivity details MOA