Neuronal acetylcholine receptor subunit alpha-7

Description:

Description
  • Accession: Q05941
  • Swissprot: ACHA7_RAT
  • Organism: Rattus norvegicus
  • Gene: Chrna7
  • Target class: Ion channel

Drug Relations:

acetylcholine
A neurotransmitter found at neuromuscular junctions, autonomic ganglia, parasympathetic effector junctions, a subset of sympathetic effector junctions, and at many sites in the central nervous system. Miochol-E (acetylcholine chloride intraocular solution) is used to obtain miosis of the iris in seconds after delivery of the lens in cataract surgery, in penetrating keratoplasty, iridectomy and other anterior segment surgery where rapid miosis may be required. Bioactivity details MOA
cytisine
RN given refers to (R)-isomer; structure Bioactivity details MOA
nicotine
Devices or delivery systems used to aid in ending a TOBACCO habit. Bioactivity details MOA
ondansetron
A competitive serotonin type 3 receptor antagonist. It is effective in the treatment of nausea and vomiting caused by cytotoxic chemotherapy drugs, including cisplatin, and has reported anxiolytic and neuroleptic properties. Bioactivity details MOA
tropisetron
An indole derivative and 5-HT3 RECEPTOR antagonist that is used for the prevention of nausea and vomiting. Bioactivity details MOA
tubocurarine
A neuromuscular blocker and active ingredient in CURARE; plant based alkaloid of Menispermaceae. Bioactivity details MOA
varenicline
A benzazepine derivative that functions as an ALPHA4-BETA2 NICOTINIC RECEPTOR partial agonist. It is used for SMOKING CESSATION. Bioactivity details MOA