Lactoylglutathione lyase

Description:

Description
  • Accession: Q04760
  • Swissprot: LGUL_HUMAN
  • Organism: Homo sapiens
  • Gene: GLO1
  • Target class: Enzyme

Drug Relations:

acemetacin
Bioactivity details MOA
indomethacin
A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES. Additional data needed to determine whether in vitro activity against SARS-CoV-2 corresponds with clinical efficacy in the treatment of COVID-19. Bioactivity details MOA
quercetin
A flavonol widely distributed in plants. It is an antioxidant, like many other phenolic heterocyclic compounds. Glycosylated forms include RUTIN and quercetrin. Bioactivity details MOA
sulfadimidine
A sulfanilamide anti-infective agent. It has a spectrum of antimicrobial action similar to other sulfonamides. Bioactivity details MOA
sulindac
A sulfinylindene derivative prodrug whose sulfinyl moiety is converted in vivo to an active NSAID analgesic. Specifically, the prodrug is converted by liver enzymes to a sulfide which is excreted in the bile and then reabsorbed from the intestine. This helps to maintain constant blood levels with reduced gastrointestinal side effects. Bioactivity details MOA
tolmetin
A non-steroidal anti-inflammatory agent (ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL) similar in mode of action to INDOMETHACIN. Bioactivity details MOA