Cholinesterase

Description:

Description
  • Accession: Q03311
  • Swissprot: CHLE_MOUSE
  • Organism: Mus musculus
  • Gene: Bche
  • Target class: Enzyme

Drug Relations:

meptazinol
A narcotic antagonist with analgesic properties. It is used for the control of moderate to severe pain. Bioactivity details MOA
phencyclidine
A hallucinogen formerly used as a veterinary anesthetic, and briefly as a general anesthetic for humans. Phencyclidine is similar to KETAMINE in structure and in many of its effects. Like ketamine, it can produce a dissociative state. It exerts its pharmacological action through inhibition of NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE). As a drug of abuse, it is known as PCP and Angel Dust. Bioactivity details MOA
physostigmine
A cholinesterase inhibitor that is rapidly absorbed through membranes. It can be applied topically to the conjunctiva. It also can cross the blood-brain barrier and is used when central nervous system effects are desired, as in the treatment of severe anticholinergic toxicity. Bioactivity details MOA
rivastigmine
A carbamate-derived reversible CHOLINESTERASE INHIBITOR that is selective for the CENTRAL NERVOUS SYSTEM and is used for the treatment of DEMENTIA in ALZHEIMER DISEASE and PARKINSON DISEASE. Bioactivity details MOA