Oxytocin receptor


  • Accession: P70536
  • Swissprot: OXYR_RAT
  • Organism: Rattus norvegicus
  • Gene: Oxtr
  • Target class: GPCR

Drug Relations:

Atosiban is a synthetic peptide which is a competitive antagonist of human oxytocin at receptor level. In human pre-term labour, atosiban at the recommended dosage antagonises uterine contractions and induces uterine quiescence. Bioactivity details MOA
octa-peptide lacking free amino group on cystine residue; RN given refers to cpd without isomeric designation Bioactivity details MOA
A synthetic analog of the pituitary hormone, ARGININE VASOPRESSIN. Its action is mediated by the VASOPRESSIN receptor V2. It has prolonged antidiuretic activity, but little pressor effects. It also modulates levels of circulating FACTOR VIII and VON WILLEBRAND FACTOR. Bioactivity details MOA
A nonapeptide hormone released from the neurohypophysis (PITUITARY GLAND, POSTERIOR). It differs from VASOPRESSIN by two amino acids at residues 3 and 8. Oxytocin acts on SMOOTH MUSCLE CELLS, such as causing UTERINE CONTRACTIONS and MILK EJECTION. Bioactivity details MOA
Bioactivity details MOA