Chloramphenicol acetyltransferase


  • Accession: P62580
  • Swissprot: CAT_SALTI
  • Organism: Salmonella typhi
  • Gene: cat
  • Target class: Enzyme

Drug Relations:

An antibiotic first isolated from cultures of Streptomyces venequelae in 1947 but now produced synthetically. It has a relatively simple structure and was the first broad-spectrum antibiotic to be discovered. It acts by interfering with bacterial protein synthesis and is mainly bacteriostatic. (From Martindale, The Extra Pharmacopoeia, 29th ed, p106) Bioactivity details MOA