Synaptosomal-associated protein 25


  • Accession: P60880
  • Swissprot: SNP25_HUMAN
  • Organism: Homo sapiens
  • Gene: SNAP25
  • Target class: Cytosolic other

Drug Relations:

botulinum toxin type A
Botulinum toxin type A (Clostridium botulinum neurotoxin) blocks peripheral acetylcholine release at presynaptic cholinergic nerve terminals by cleaving SNAP-25, a protein integral to the successful docking and release of acetylcholine from vesicles situated within the nerve endings, thereby leading to denervation of the muscle and a flaccid paralysis. Bioactivity details MOA
PrabotulinumtoxinA-xvfs is an acetylcholine release inhibitor and a neuromuscular blocking agent Bioactivity details MOA