Methionine aminopeptidase 1


  • Accession: P53582
  • Swissprot: MAP11_HUMAN
  • Organism: Homo sapiens
  • Gene: METAP1
  • Target class: Enzyme

Drug Relations:

has antitubercular activity Bioactivity details MOA
Bioactivity details MOA
An antiseptic with mild fungistatic, bacteriostatic, anthelmintic, and amebicidal action. It is also used as a reagent and metal chelator, as a carrier for radio-indium for diagnostic purposes, and its halogenated derivatives are used in addition as topical anti-infective agents and oral antiamebics. Bioactivity details MOA
2-Substituted benzimidazole first introduced in 1962. It is active against a variety of nematodes and is the drug of choice for STRONGYLOIDIASIS. It has CENTRAL NERVOUS SYSTEM side effects and hepatototoxic potential. (From Smith and Reynard, Textbook of Pharmacology, 1992, p919) Bioactivity details MOA