4-aminobutyrate aminotransferase, mitochondrial

Description:

Description
  • Accession: P50554
  • Swissprot: GABT_RAT
  • Organism: Rattus norvegicus
  • Gene: Abat
  • Target class: Unclassified

Drug Relations:

vigabatrin
The precise mechanism of vigabatrin's anti-seizure effect is unknown, but it is believed to be the result of its action as an irreversible inhibitor of gamma-aminobutyric acid transaminase (GABA-T), the enzyme responsible for the metabolism of the inhibitory neurotransmitter GABA. This action results in increased levels of GABA in the central nervous system. Bioactivity details MOA