Glutamate receptor ionotropic, kainate 3

Description:

Description
  • Accession: P42264
  • Swissprot: GRIK3_RAT
  • Organism: Rattus norvegicus
  • Gene: Grik3
  • Target class: Ion channel

Drug Relations:

glutamic acid
A non-essential amino acid naturally occurring in the L-form. Glutamic acid is the most common excitatory neurotransmitter in the CENTRAL NERVOUS SYSTEM. Bioactivity details MOA
kainic acid
(2S-(2 alpha,3 beta,4 beta))-2-Carboxy-4-(1-methylethenyl)-3-pyrrolidineacetic acid. Ascaricide obtained from the red alga Digenea simplex. It is a potent excitatory amino acid agonist at some types of excitatory amino acid receptors and has been used to discriminate among receptor types. Like many excitatory amino acid agonists it can cause neurotoxicity and has been used experimentally for that purpose. Bioactivity details MOA