Malate dehydrogenase, cytoplasmic


  • Accession: P40925
  • Swissprot: MDHC_HUMAN
  • Organism: Homo sapiens
  • Gene: MDH1
  • Target class: Enzyme

Drug Relations:

An imidazole derivative with a broad spectrum of antimycotic activity. It inhibits biosynthesis of the sterol ergostol, an important component of fungal CELL MEMBRANES. Its action leads to increased membrane permeability and apparent disruption of enzyme systems bound to the membrane. Bioactivity details MOA
A potent, non-nucleoside reverse transcriptase inhibitor with activity specific for HIV-1. Bioactivity details MOA
An imidazole derivative that is commonly used as a topical antifungal agent. Bioactivity details MOA
An imidazole antifungal agent that is used topically and by intravenous infusion. Bioactivity details MOA
A potent calcium channel blockader with marked vasodilator action. It has antihypertensive properties and is effective in the treatment of angina and coronary spasms without showing cardiodepressant effects. It has also been used in the treatment of asthma and enhances the action of specific antineoplastic agents. Bioactivity details MOA
Bioactivity details MOA