Aryl hydrocarbon receptor


  • Accession: P35869
  • Swissprot: AHR_HUMAN
  • Organism: Homo sapiens
  • Gene: AHR
  • Target class: Transcription factor

Drug Relations:

An aminoquinoline that is given by mouth to produce a radical cure and prevent relapse of vivax and ovale malarias following treatment with a blood schizontocide. It has also been used to prevent transmission of falciparum malaria by those returning to areas where there is a potential for re-introduction of malaria. Adverse effects include anemias and GI disturbances. (From Martindale, The Extra Pharmacopeia, 30th ed, p404) Bioactivity details MOA