Choline O-acetyltransferase


  • Accession: P32738
  • Swissprot: CLAT_RAT
  • Organism: Rattus norvegicus
  • Gene: Chat
  • Target class: Enzyme

Drug Relations:

An indan and piperidine derivative that acts as a selective and reversible inhibitor of ACETYLCHOLINESTERASE. Donepezil is highly selective for the central nervous system and is used in the management of mild to moderate DEMENTIA in ALZHEIMER DISEASE. Bioactivity details MOA
A cholinesterase inhibitor that crosses the blood-brain barrier. Tacrine has been used to counter the effects of muscle relaxants, as a respiratory stimulant, and in the treatment of Alzheimer's disease and other central nervous system disorders. Bioactivity details MOA