Prostaglandin E2 receptor EP4 subtype


  • Accession: P32240
  • Swissprot: PE2R4_MOUSE
  • Organism: Mus musculus
  • Gene: Ptger4
  • Target class: GPCR

Drug Relations:

A potent vasodilator agent that increases peripheral blood flow. Bioactivity details MOA
The most common and most biologically active of the mammalian prostaglandins. It exhibits most biological activities characteristic of prostaglandins and has been used extensively as an oxytocic agent. The compound also displays a protective effect on the intestinal mucosa. Bioactivity details MOA
An eicosanoid, derived from the cyclooxygenase pathway of arachidonic acid metabolism. It is a stable and synthetic analog of EPOPROSTENOL, but with a longer half-life than the parent compound. Its actions are similar to prostacyclin. Iloprost produces vasodilation and inhibits platelet aggregation. Bioactivity details MOA