Cholecystokinin receptor type A


  • Accession: P32238
  • Swissprot: CCKAR_HUMAN
  • Organism: Homo sapiens
  • Gene: CCKAR
  • Target class: GPCR

Drug Relations:

A specific decapeptide obtained from the skin of Hila caerulea, an Australian amphibian. Caerulein is similar in action and composition to CHOLECYSTOKININ. It stimulates gastric, biliary, and pancreatic secretion; and certain smooth muscle. It is used in paralytic ileus and as diagnostic aid in pancreatic malfunction. Bioactivity details MOA
An anxiolytic benzodiazepine derivative with anticonvulsant, sedative, and amnesic properties. It has also been used in the symptomatic treatment of alcohol withdrawal. Bioactivity details MOA
a CCK receptor antagonist; structure given in first source Bioactivity details MOA
cholecystokinin receptor antagonist; RN refers to (+-)-isomer Bioactivity details MOA
A cyclodecane isolated from the bark of the Pacific yew tree, TAXUS BREVIFOLIA. It stabilizes MICROTUBULES in their polymerized form leading to cell death. Bioactivity details MOA
An octapeptide hormone present in the intestine and brain. When secreted from the gastric mucosa, it stimulates the release of bile from the gallbladder and digestive enzymes from the pancreas. Bioactivity details MOA