NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial


  • Accession: P28331
  • Swissprot: NDUS1_HUMAN
  • Organism: Homo sapiens
  • Gene: NDUFS1
  • Target class: Enzyme

Drug Relations:

A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289) Bioactivity details MOA