Genome polyprotein

Description:

Description
  • Accession: P27958
  • Swissprot: POLG_HCVH
  • Organism: Hepatitis C virus genotype 1a (isolate H)
  • Target class: Polyprotein

Drug Relations:

asunaprevir
an NS3 protease inhibitor against hepatitis C virus Bioactivity details MOA
daclatasvir
an HCV NS5A inhibitor Bioactivity details MOA
elbasvir
inhibits NS5A protein of hepatitis C virus Bioactivity details MOA
grazoprevir
has antiviral activity Bioactivity details MOA
ledipasvir
an inhibitor of the HCV NS5A protein, which is required for viral replication Bioactivity details MOA
ombitasvir
inhibits HCV NS5A protein Bioactivity details MOA
simeprevir
Oral HCV-PROTEASE INHIBITOR effective against hepatitis C virus (HCV) serine protease NS3/4A. It is used in the treatment of chronic hepatitis C (Antivirals) genotype 1 infection in adults with compensated liver disease, including CIRRHOSIS. Bioactivity details MOA
sofosbuvir
A uridine monophosphate analog inhibitor of HEPATITIS C VIRUS (HCV) polymerase NS5B that is used as an ANTIVIRAL AGENT in the treatment of CHRONIC HEPATITIS C. Bioactivity details MOA
velpatasvir
pan-genotypic NS5A inhibitor for the treatment of chronic genotype 1-6 hepatitis C virus (HCV) infection Bioactivity details MOA