Endothelin-1 receptor

Description:

Description
  • Accession: P26684
  • Swissprot: EDNRA_RAT
  • Organism: Rattus norvegicus
  • Gene: Ednra
  • Target class: GPCR

Drug Relations:

bosentan
a specific and competitive antagonist at endothelin receptor types ETA and ETB, has a slightly higher affinity for ETA receptors than for ETB receptors, indicated for the treatment of pulmonary arterial hypertension Bioactivity details MOA
sitaxentan
endothelin A receptor antagonist Bioactivity details MOA
sulfafurazole
A short-acting sulfonamide antibacterial with activity against a wide range of gram- negative and gram-positive organisms. Bioactivity details MOA
sulfamethoxazole
A bacteriostatic antibacterial agent that interferes with folic acid synthesis in susceptible bacteria. Its broad spectrum of activity has been limited by the development of resistance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p208) Bioactivity details MOA
sulfathiazole
A sulfathiazole compound that is used as a short-acting anti-infective agent. It is no longer commonly used systemically due to its toxicity, but may still be applied topically in combination with other drugs for the treatment of vaginal and skin infections, and is still used in veterinary medicine. Bioactivity details MOA
sulfisoxazole acetyl
Bioactivity details MOA