Endothelin B receptor

Description:

Description
  • Accession: P24530
  • Swissprot: EDNRB_HUMAN
  • Organism: Homo sapiens
  • Gene: EDNRB
  • Target class: GPCR

Drug Relations:

bosentan
a specific and competitive antagonist at endothelin receptor types ETA and ETB, has a slightly higher affinity for ETA receptors than for ETB receptors, indicated for the treatment of pulmonary arterial hypertension Bioactivity details MOA
macitentan
an endothelin receptor antagonist that prevents the binding of ET-1 to both ETA and ETB receptors, macitentan displays high affinity and sustained occupancy of the ET receptors in human pulmonary arterial smooth muscle cells Bioactivity details MOA
ambrisentan
an endothelin receptor antagonist that is selective for the endothelin type-A (ETA) receptor Bioactivity details MOA
sitaxentan
endothelin A receptor antagonist Bioactivity details MOA
sulfafurazole
A short-acting sulfonamide antibacterial with activity against a wide range of gram- negative and gram-positive organisms. Bioactivity details MOA
sulfisoxazole acetyl
Bioactivity details MOA