Peptidyl-prolyl cis-trans isomerase B


  • Accession: P23284
  • Swissprot: PPIB_HUMAN
  • Organism: Homo sapiens
  • Gene: PPIB
  • Target class: Enzyme

Drug Relations:

A cyclic undecapeptide from an extract of soil fungi. It is a powerful immunosupressant with a specific action on T-lymphocytes. It is used for the prophylaxis of graft rejection in organ and tissue transplantation. (From Martindale, The Extra Pharmacopoeia, 30th ed). Bioactivity details MOA