Thyroid hormone receptor beta

Description:

Description
  • Accession: P18113
  • Swissprot: THB_RAT
  • Organism: Rattus norvegicus
  • Gene: Thrb
  • Target class: Transcription factor

Drug Relations:

dextrothyroxine
The dextrorotary isomer of the synthetic THYROXINE. Bioactivity details MOA
levothyroxine
The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism. Bioactivity details MOA
liothyronine
A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3. Bioactivity details MOA
tiratricol
Bioactivity details MOA