Beta-galactosidase

Description:

Description
  • Accession: P16278
  • Swissprot: BGAL_HUMAN
  • Organism: Homo sapiens
  • Gene: GLB1
  • Target class: Enzyme

Drug Relations:

migalastat
Migalastat is a pharmacological chaperone that is designed to selectively and reversibly bind with high affinity to the active sites of certain mutant forms of alpha-Gal A, the genotypes of which are referred to as amenable mutations. Migalastat binding stabilizes these mutant forms of alpha-Gal A in the endoplasmic reticulum and facilitates their proper trafficking to lysosomes where dissociation of migalastat restores alpha-Gal A activity, leading to the catabolism of GL-3 and related substrates. Bioactivity details MOA
rose bengal
A bright bluish pink compound that has been used as a dye, biological stain, and diagnostic aid. Bioactivity details MOA