Voltage-dependent L-type calcium channel subunit alpha-1C

Description:

Description
  • Accession: P15381
  • Swissprot: CAC1C_RABIT
  • Organism: Oryctolagus cuniculus
  • Gene: CACNA1C
  • Target class: Ion channel

Drug Relations:

bepridil
A long-acting calcium-blocking agent with significant anti-anginal activity. The drug produces significant coronary vasodilation and modest peripheral effects. It has antihypertensive and selective anti-arrhythmia activities and acts as a calmodulin antagonist. Bioactivity details MOA
diltiazem
A benzothiazepine derivative with vasodilating action due to its antagonism of the actions of CALCIUM ion on membrane functions. Bioactivity details MOA
isradipine
A potent antagonist of CALCIUM CHANNELS that is highly selective for VASCULAR SMOOTH MUSCLE. It is effective in the treatment of chronic stable angina pectoris, hypertension, and congestive cardiac failure. Bioactivity details MOA
nifedipine
A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure. Bioactivity details MOA
verapamil
A calcium channel blocker that is a class IV anti-arrhythmia agent. Bioactivity details MOA