Interleukin-1 receptor type 1


  • Accession: P14778
  • Swissprot: IL1R1_HUMAN
  • Organism: Homo sapiens
  • Gene: IL1R1
  • Target class: Membrane receptor

Drug Relations:

A ligand that binds to but fails to activate the INTERLEUKIN 1 RECEPTOR. It plays an inhibitory role in the regulation of INFLAMMATION and FEVER. Several isoforms of the protein exist due to multiple ALTERNATIVE SPLICING of its mRNA. Bioactivity details MOA
Semisynthetic ampicillin-derived acylureido penicillin. It has been proposed for infections with certain anaerobes and may be useful in inner ear, bile, and CNS infections. Bioactivity details MOA