Sodium/potassium-transporting ATPase subunit beta-2


  • Accession: P14415
  • Swissprot: AT1B2_HUMAN
  • Organism: Homo sapiens
  • Gene: ATP1B2
  • Target class: Transporter

Drug Relations:

Cardioactive derivatives of lanatoside A or of DIGITOXIN. They are used for fast digitalization in congestive heart failure. Bioactivity details MOA
Deacetyllanatoside C. A cardiotonic glycoside from the leaves of Digitalis lanata. Bioactivity details MOA
A cardiotonic glycoside obtained mainly from Digitalis lanata; it consists of three sugars and the aglycone DIGOXIGENIN. Digoxin has positive inotropic and negative chronotropic activity. It is used to control ventricular rate in ATRIAL FIBRILLATION and in the management of congestive heart failure with atrial fibrillation. Its use in congestive heart failure and sinus rhythm is less certain. The margin between toxic and therapeutic doses is small. (From Martindale, The Extra Pharmacopoeia, 30th ed, p666) Bioactivity details MOA
A cardiac glycoside sometimes used in place of DIGOXIN. It has a longer half-life than digoxin; toxic effects, which are similar to those of digoxin, are longer lasting. (From Martindale, The Extra Pharmacopoeia, 30th ed, p665) Bioactivity details MOA