Estradiol 17-beta-dehydrogenase 1

Description:

Description
  • Accession: P14061
  • Swissprot: DHB1_HUMAN
  • Organism: Homo sapiens
  • Gene: HSD17B1
  • Target class: Enzyme

Drug Relations:

acetoxolone
Bioactivity details MOA
estrone
An aromatized C18 steroid with a 3-hydroxyl group and a 17-ketone, a major mammalian estrogen. It is converted from ANDROSTENEDIONE directly, or from TESTOSTERONE via ESTRADIOL. In humans, it is produced primarily by the cyclic ovaries, PLACENTA, and the ADIPOSE TISSUE of men and postmenopausal women. Bioactivity details MOA