Gamma-aminobutyric acid receptor subunit alpha-2

Description:

Description
  • Accession: P10063
  • Swissprot: GBRA2_BOVIN
  • Organism: Bos taurus
  • Gene: GABRA2
  • Target class: Ion channel

Drug Relations:

chlordiazepoxide
An anxiolytic benzodiazepine derivative with anticonvulsant, sedative, and amnesic properties. It has also been used in the symptomatic treatment of alcohol withdrawal. Bioactivity details MOA
clonazepam
An anticonvulsant used for several types of seizures, including myotonic or atonic seizures, photosensitive epilepsy, and absence seizures, although tolerance may develop. It is seldom effective in generalized tonic-clonic or partial seizures. The mechanism of action appears to involve the enhancement of GAMMA-AMINOBUTYRIC ACID receptor responses. Bioactivity details MOA
diazepam
A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of GAMMA-AMINOBUTYRIC ACID activity. Bioactivity details MOA
flumazenil
A potent benzodiazepine receptor antagonist. Since it reverses the sedative and other actions of benzodiazepines, it has been suggested as an antidote to benzodiazepine overdoses. Bioactivity details MOA
nitrazepam
A benzodiazepine derivative used as an anticonvulsant and hypnotic. Bioactivity details MOA