Dihydropteroate synthase

Description:

Description
  • Accession: P0AC13
  • Swissprot: DHPS_ECOLI
  • Organism: Escherichia coli (strain K12)
  • Gene: folP
  • Target class: Enzyme

Drug Relations:

mafenide
A sulfonamide that inhibits the enzyme CARBONIC ANHYDRASE and is used as a topical anti-bacterial agent, especially in burn therapy. Bioactivity details MOA
sulfacetamide
An anti-bacterial agent that is used topically to treat skin infections and orally for urinary tract infections. Bioactivity details MOA
sulfadiazine
One of the short-acting SULFONAMIDES used in combination with PYRIMETHAMINE to treat toxoplasmosis in patients with acquired immunodeficiency syndrome and in newborns with congenital infections. Bioactivity details MOA
sulfadiazine silver
Antibacterial used topically in burn therapy. Bioactivity details MOA
sulfadimidine
A sulfanilamide anti-infective agent. It has a spectrum of antimicrobial action similar to other sulfonamides. Bioactivity details MOA
sulfafurazole
A short-acting sulfonamide antibacterial with activity against a wide range of gram- negative and gram-positive organisms. Bioactivity details MOA
sulfalene
Long-acting plasma-bound sulfonamide used for respiratory and urinary tract infections and also for malaria. Bioactivity details MOA
sulfamerazine
A sulfanilamide that is used as an antibacterial agent. Bioactivity details MOA
sulfameter
Long acting sulfonamide used in leprosy, urinary, and respiratory tract infections. Bioactivity details MOA
sulfamethizole
A sulfathiazole antibacterial agent. Bioactivity details MOA
sulfamethoxazole
A bacteriostatic antibacterial agent that interferes with folic acid synthesis in susceptible bacteria. Its broad spectrum of activity has been limited by the development of resistance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p208) Bioactivity details MOA
sulfanilamide
Sulfanilamide has been a useful ingredient of vaginal formulations for about four decades. It blocks certain metabolic processes essential for the growth of susceptible bacteria. Bioactivity details MOA
sulfaphenazole
A sulfonilamide anti-infective agent. Bioactivity details MOA
sulfapyridine
Antibacterial, potentially toxic, used to treat certain skin diseases. Bioactivity details MOA
sulfathiazole
A sulfathiazole compound that is used as a short-acting anti-infective agent. It is no longer commonly used systemically due to its toxicity, but may still be applied topically in combination with other drugs for the treatment of vaginal and skin infections, and is still used in veterinary medicine. Bioactivity details MOA
sulfisoxazole acetyl
Bioactivity details MOA