Leukotriene A-4 hydrolase

Description:

Description
  • Accession: P09960
  • Swissprot: LKHA4_HUMAN
  • Organism: Homo sapiens
  • Gene: LTA4H
  • Target class: Enzyme

Drug Relations:

captopril
A potent and specific inhibitor of PEPTIDYL-DIPEPTIDASE A. It blocks the conversion of ANGIOTENSIN I to ANGIOTENSIN II, a vasoconstrictor and important regulator of arterial blood pressure. Captopril acts to suppress the RENIN-ANGIOTENSIN SYSTEM and inhibits pressure responses to exogenous angiotensin. Bioactivity details MOA
ubenimex
growth inhibitor; RN given refers to ((L-Leu)-(S-(R*,S*)))-isomer; structure Bioactivity details MOA
zileuton
an orally active inhibitor of 5-lipoxygenase, the enzyme that catalyzes the formation of leukotrienes from arachidonic acid Bioactivity details MOA