Eukaryotic translation initiation factor 4E


  • Accession: P06730
  • Swissprot: IF4E_HUMAN
  • Organism: Homo sapiens
  • Gene: EIF4E
  • Target class: Nuclear other

Drug Relations:

A macrolide compound obtained from Streptomyces hygroscopicus that acts by selectively blocking the transcriptional activation of cytokines thereby inhibiting cytokine production. It is bioactive only when bound to IMMUNOPHILINS. Sirolimus is a potent immunosuppressant and possesses both antifungal and antineoplastic properties. Bioactivity details MOA