Protein kinase C beta type


  • Accession: P05771
  • Swissprot: KPCB_HUMAN
  • Organism: Homo sapiens
  • Gene: PRKCB
  • Target class: Kinase

Drug Relations:

ingenol mebutate
protein kinase C agonist and antineoplastic Bioactivity details MOA
inhibits protein kinase C beta Bioactivity details MOA
A polyanionic compound with an unknown mechanism of action. It is used parenterally in the treatment of African trypanosomiasis and it has been used clinically with diethylcarbamazine to kill the adult Onchocerca. (From AMA Drug Evaluations Annual, 1992, p1643) It has also been shown to have potent antineoplastic properties. Bioactivity details MOA