T-cell surface glycoprotein CD4


  • Accession: P01730
  • Swissprot: CD4_HUMAN
  • Organism: Homo sapiens
  • Gene: CD4
  • Target class: Membrane receptor

Drug Relations:

Ibalizumab-uiyk, a recombinant humanized monoclonal antibody, blocks HIV-1 from infecting CD4+ T cells by binding to domain 2 of CD4 and interfering with post-attachment steps required for the entry of HIV-1 virus particles into host cells and preventing the viral transmission that occurs via cell-cell fusion Bioactivity details MOA