Interferon gamma


  • Accession: P01579
  • Swissprot: IFNG_HUMAN
  • Organism: Homo sapiens
  • Gene: IFNG
  • Target class: Cytokine

Drug Relations:

Emapalumab-lzsg is a monoclonal antibody that binds to and neutralizes interferon gamma (IFNgamma). Nonclinical data suggest that IFNgamma plays a pivotal role in the pathogenesis of HLH by being hypersecreted. Bioactivity details MOA
A glucocorticoid used in the management of ASTHMA, the treatment of various skin disorders, and allergic RHINITIS. Bioactivity details MOA
an ascomycin derivative; mechanism of action involves calcineurin inhibition, blockage of T cell activation, blocking signal transduction pathways in T cells, and inhibition of the synthesis of inflammatory cytokines, specifically Th1- and Th2-type cytokines Bioactivity details MOA
A macrolide isolated from the culture broth of a strain of Streptomyces tsukubaensis that has strong immunosuppressive activity in vivo and prevents the activation of T-lymphocytes in response to antigenic or mitogenic stimulation in vitro. Bioactivity details MOA