Glutathione reductase, mitochondrial

Description:

Description
  • Accession: P00390
  • Swissprot: GSHR_HUMAN
  • Organism: Homo sapiens
  • Gene: GSR
  • Target class: Enzyme

Drug Relations:

carmustine
A cell-cycle phase nonspecific alkylating antineoplastic agent. It is used in the treatment of brain tumors and various other malignant neoplasms. (From Martindale, The Extra Pharmacopoeia, 30th ed, p462) This substance may reasonably be anticipated to be a carcinogen according to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (From Merck Index, 11th ed) Bioactivity details MOA
glutamic acid
A non-essential amino acid naturally occurring in the L-form. Glutamic acid is the most common excitatory neurotransmitter in the CENTRAL NERVOUS SYSTEM. Bioactivity details MOA
lysine
An essential amino acid. It is often added to animal feed. Bioactivity details MOA
menadione
Bioactivity details MOA
methylthioninium chloride
A compound consisting of dark green crystals or crystalline powder, having a bronze-like luster. Solutions in water or alcohol have a deep blue color. Methylene blue is used as a bacteriologic stain and as an indicator. It inhibits GUANYLATE CYCLASE, and has been used to treat cyanide poisoning and to lower levels of METHEMOGLOBIN. Bioactivity details MOA
nifedipine
A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure. Bioactivity details MOA