Nuclear receptor subfamily 1 group I member 3


  • Accession: O35627
  • Swissprot: NR1I3_MOUSE
  • Organism: Mus musculus
  • Gene: Nr1i3
  • Target class: Unclassified

Drug Relations:

A histamine H1 antagonist used in the treatment of motion sickness, vertigo, and nausea during pregnancy and radiation sickness. Bioactivity details MOA
A potent androgenic steroid and major product secreted by the LEYDIG CELLS of the TESTIS. Its production is stimulated by LUTEINIZING HORMONE from the PITUITARY GLAND. In turn, testosterone exerts feedback control of the pituitary LH and FSH secretion. Depending on the tissues, testosterone can be further converted to DIHYDROTESTOSTERONE or ESTRADIOL. Bioactivity details MOA