Voltage-dependent P/Q-type calcium channel subunit alpha-1A


  • Accession: O00555
  • Swissprot: CAC1A_HUMAN
  • Organism: Homo sapiens
  • Gene: CACNA1A
  • Target class: Ion channel

Drug Relations:

A long-acting calcium-blocking agent with significant anti-anginal activity. The drug produces significant coronary vasodilation and modest peripheral effects. It has antihypertensive and selective anti-arrhythmia activities and acts as a calmodulin antagonist. Bioactivity details MOA
One of the long-acting synthetic ANTIDIARRHEALS; it is not significantly absorbed from the gut, and has no effect on the adrenergic system or central nervous system, but may antagonize histamine and interfere with acetylcholine release locally. Bioactivity details MOA
A dihydropyridine calcium channel antagonist that acts as a potent arterial vasodilator and antihypertensive agent. It is also effective in patients with cardiac failure and angina. Bioactivity details MOA