clorprenaline 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
bronchodilators, phenethylamine derivatives 714 3811-25-4

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • clorprenaline
  • isoprofenamine
  • isoprophenamine
  • clorprenaline hydrochloride
  • clorprenaline HCl
  • Molecular weight: 213.71
  • Formula: C11H16ClNO
  • CLOGP: 2.13
  • LIPINSKI: 0
  • HAC: 2
  • HDO: 2
  • TPSA: 32.26
  • ALOGS: -2.35
  • ROTB: 4

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
MeSH PA D018927 Anti-Asthmatic Agents
MeSH PA D001993 Bronchodilator Agents
MeSH PA D018373 Peripheral Nervous System Agents
MeSH PA D019141 Respiratory System Agents
MeSH PA D013566 Sympathomimetics
CHEBI has role CHEBI:35522 beta-adrenergic agonists
CHEBI has role CHEBI:35523 bronchodilator
CHEBI has role CHEBI:35524 sympathomimetic

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 8.64 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])
Mechanism
action
Bioact sourceMoA source
Beta-1 adrenergic receptor GPCR Ki 5.83 DRUG MATRIX
Beta-2 adrenergic receptor GPCR Ki 5.86 DRUG MATRIX

External reference:

IDSource
D01835 KEGG_DRUG
C0055943 UMLSCUI
CHEBI:134887 CHEBI
CHEMBL1902627 ChEMBL_ID
2810 PUBCHEM_CID
C004350 MESH_SUPPLEMENTAL_RECORD_UI
1696 INN_ID
5588-22-7 SECONDARY_CAS_RN
3W4327W76O UNII
008203 NDDF
008204 NDDF
96260001 SNOMEDCT_US
CHEMBL3989576 ChEMBL_ID
CHEMBL2106149 ChEMBL_ID

Pharmaceutical products:

None