clopamide 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
diuretics, sulfamoylbenzoic acid derivatives 706 636-54-4

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • brinedine
  • clopamide
  • chlosudimeprimyl
  • clopamidum
  • brinaldix
A sulfamoylbenzamide piperidine. It is considered a thiazide-like diuretic.
  • Molecular weight: 345.84
  • Formula: C14H20ClN3O3S
  • CLOGP: 2.37
  • LIPINSKI: 0
  • HAC: 6
  • HDO: 2
  • TPSA: 92.50
  • ALOGS: -3.40
  • ROTB: 3

Drug dosage:

DoseUnitRoute
10 mg O
10 mg O

ADMET properties:

PropertyValueReference
BDDCS (Biopharmaceutical Drug Disposition Classification System) 3 Hosey CM, Chan R, Benet LZ

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC C03BA03 CARDIOVASCULAR SYSTEM
DIURETICS
LOW-CEILING DIURETICS, EXCL. THIAZIDES
Sulfonamides, plain
ATC C03BB03 CARDIOVASCULAR SYSTEM
DIURETICS
LOW-CEILING DIURETICS, EXCL. THIAZIDES
Sulfonamides and potassium in combination
MeSH PA D004232 Diuretics
MeSH PA D045283 Natriuretic Agents

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 8.61 acidic
pKa2 11.42 acidic
pKa3 3.76 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
N0000167202 NUI
D02460 KEGG_DRUG
2603 RXNORM
C0009025 UMLSCUI
CHEBI:94521 CHEBI
CHEMBL1361347 ChEMBL_ID
DB13792 DRUGBANK_ID
D003005 MESH_DESCRIPTOR_UI
12492 PUBCHEM_CID
1517 INN_ID
17S83WON0I UNII
003711 NDDF
395940005 SNOMEDCT_US
429462003 SNOMEDCT_US

Pharmaceutical products:

None