cinolazepam Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
diazepam derivatives 656 75696-02-5

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • cinolazepam
  • gerodorm
  • Molecular weight: 357.77
  • Formula: C18H13ClFN3O2
  • CLOGP: 1.91
  • LIPINSKI: 0
  • HAC: 5
  • HDO: 1
  • TPSA: 76.69
  • ALOGS: -4.48
  • ROTB: 3

Drug dosage:

None

ADMET properties:

PropertyValueReference
BA (Bioavailability) 95 % Kim MT, Sedykh A, Chakravarti SK, Saiakhov RD, Zhu H

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

Pharmacologic Action:

SourceCodeDescription
ATC N05CD13 NERVOUS SYSTEM
PSYCHOLEPTICS
HYPNOTICS AND SEDATIVES
Benzodiazepine derivatives
CHEBI has role CHEBI:35623 antiepileptic
CHEBI has role CHEBI:35717 sedatives

Drug Use (View source of the data)

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 9.21 acidic
pKa2 1.2 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D07328 KEGG_DRUG
C0164835 UMLSCUI
CHEBI:59514 CHEBI
CHEMBL2104926 ChEMBL_ID
DB01594 DRUGBANK_ID
C053781 MESH_SUPPLEMENTAL_RECORD_UI
3033621 PUBCHEM_CID
5051 INN_ID
68P0556B0U UNII

Pharmaceutical products:

None