eptotermin alfa 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
bone morphogenic proteins 5175 129805-33-0

Description:

MoleculeDescription

Synonyms:

  • eptotermin alfa
  • osigraft
  • human recombinant bone morphogenetic protein 7
  • rhBMP-7
an osteoinductive initiates bone formation through the induction of cellular differentiation in mesenchymal cells, which are recruited to the implant site from bone marrow periosteum and muscle, used for treatment of non-union of bone fractures
  • Molecular weight: 31361.54
  • Formula: C1366H2122N394O416S20
  • CLOGP:
  • LIPINSKI: None
  • HAC: None
  • HDO: None
  • TPSA:
  • ALOGS:
  • ROTB: None

Drug dosage:

None

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
May 17, 2001 EMA Olympus Biotech International Limited

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC M05BC02 MUSCULO-SKELETAL SYSTEM
DRUGS FOR TREATMENT OF BONE DISEASES
DRUGS AFFECTING BONE STRUCTURE AND MINERALIZATION
Bone morphogenetic proteins

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Nonunion of fracture indication 302941001




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
IT063R5MY0 UNII
D07437 KEGG_DRUG
C1445625 UMLSCUI
CHEMBL2108594 ChEMBL_ID
DB11631 DRUGBANK_ID
7989 INN_ID
012781 NDDF
412029000 SNOMEDCT_US

Pharmaceutical products:

None